Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718978 | 1.00 | HCAR2 (0.38) | HCAR2ATMTSHRKMT2ATHRB | |
| SCHEMBL8790610 | 0.93 | TSHR (0.35) | HCAR2TSHRKMT2ANFKB1CYP2C19 | |
| SCHEMBL8790619 | 0.93 | TSHR (0.35) | HCAR2TSHRKMT2ANFKB1CYP2C19 | |
| SCHEMBL10707940 | 0.93 | TSHR (0.35) | HCAR2TSHRKMT2ANFKB1CYP2C19 | |
| SCHEMBL5422213 | 0.85 | TSHR (0.33) | TSHRKMT2AGAAHTTALDH1A1 | |
| SCHEMBL5422202 | 0.85 | TSHR (0.33) | TSHRKMT2AGAAHTTALDH1A1 | |
| SCHEMBL13588319 | 0.84 | GAA (0.43) | ATMTSHRKMT2AGAAHTT | |
| SCHEMBL21911139 | 0.81 | TSHR (0.31) | TSHRKMT2AGAAHTT | |
| SCHEMBL69507 | 0.79 | TSHR (0.33) | TSHRKMT2ANFKB1CYP2C19CYP2D6 | |
| SCHEMBL18534067 | 0.79 | TSHR (0.33) | TSHRKMT2ANFKB1CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135986-A | Graft polymers of styrene or A-methylstyrene and a comonomer on a core of elastomer modified by a steric hindered unsaturated 2,2,6,6-tetramethylpiperidine compoune; photostability | CIBA-GEIGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |