Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 19/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724051 | 1.00 | PTAFR (0.44) | PTAFR | |
| SCHEMBL9724049 | 1.00 | PTAFR (0.44) | PTAFR | |
| SCHEMBL9719017 | 1.00 | PTAFR (0.44) | PTAFR | |
| SCHEMBL9719122 | 1.00 | PTAFR (0.44) | PTAFR | |
| SCHEMBL9719881 | 1.00 | PTAFR (0.44) | PTAFR | |
| SCHEMBL9719095 | 0.90 | LMNA (0.38) | PTAFR | |
| SCHEMBL9719092 | 0.90 | LMNA (0.38) | PTAFR | |
| SCHEMBL9719107 | 0.89 | PTAFR (0.41) | PTAFR | |
| SCHEMBL9719887 | 0.88 | PTAFR (0.44) | PTAFR | |
| SCHEMBL10641571 | 0.88 | PTAFR (0.44) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257921-B1 | NEW 1,3-DIARYL CYCLOPENTANES AND DERIVATIVES THEREOF AS PAF ANTAGONISTS | MERCK & CO. INC. (US) | 1992-04-15 | — | — | EP | disclosed |
| EP-0257921-A2 | New 1,3-diaryl cyclopentanes and derivatives thereof as paf antagonists | MERCK & CO. INC. (US) | 1988-03-02 | — | — | EP | disclosed |