Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719292 | 1.00 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6CYP19A1 | |
| SCHEMBL7332379 | 1.00 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6CYP19A1 | |
| Hydrochloric Acid SCHEMBL11879766 | 0.98 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3CYP2D6CYP19A1 | |
| SCHEMBL7327733 | 0.94 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6CYP19A1 | |
| Hydrochloric Acid SCHEMBL11873137 | 0.93 | IDO1 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6ALDH1A1 | |
| SCHEMBL7328111 | 0.89 | PSEN1 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7328106 | 0.89 | PSEN1 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7328837 | 0.83 | NPC1 (0.33) | CYP2D6 | |
| SCHEMBL7325274 | 0.83 | NPC1 (0.33) | CYP2D6 | |
| SCHEMBL7327602 | 0.83 | NPC1 (0.33) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370320-B1 | LACTAMIMIDES IN THE TREATMENT OF DRUG-RESISTANT PROTOZOAL INFECTIONS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-09-30 | — | — | EP | disclosed |