Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 11/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987278 | 1.00 | HCAR2 (0.54) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL9719311 | 1.00 | HCAR2 (0.54) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL9615496 | 0.89 | HCAR2 (0.45) | HCAR2TSHRALDH1A1KEAP1NFE2L2 | |
| SCHEMBL6049197 | 0.89 | HCAR2 (0.45) | HCAR2TSHRALDH1A1KEAP1NFE2L2 | |
| SCHEMBL16004844 | 0.89 | HCAR2 (0.45) | HCAR2TSHRALDH1A1KEAP1NFE2L2 | |
| SCHEMBL29406881 | 0.85 | HCAR2 (0.54) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL31246345 | 0.81 | HCAR2 (0.35) | HCAR2KEAP1NFE2L2ATM | |
| SCHEMBL2144101 | 0.80 | NFE2L2 (0.65) | HCAR2TP53ALDH1A1TDP1KDM4E | |
| SCHEMBL2144386 | 0.80 | NFE2L2 (0.65) | HCAR2TP53ALDH1A1TDP1KDM4E | |
| SCHEMBL2144096 | 0.80 | NFE2L2 (0.65) | HCAR2TP53ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | claimed |
| EP-0244835-A2 | Langmuir-Blodgett ultrathin membrane of polyfumurate | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1987-11-11 | — | — | EP | claimed |
| EP-0244835-A2 | Langmuir-Blodgett ultrathin membrane of polyfumurate | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1987-11-11 | — | — | EP | disclosed |