Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395807 | 0.82 | OPRM1 (0.41) | OPRM1DRD3DRD4DRD2CYP1A2 | |
| SCHEMBL14097833 | 0.82 | CYP2C19 (0.51) | OPRM1DRD3DRD4DRD2CYP1A2 | |
| SCHEMBL10392372 | 0.82 | CHRM3 (0.55) | OPRM1DRD3DRD2CHRM2CHRM1 | |
| SCHEMBL7170152 | 0.78 | OPRM1 (0.49) | OPRM1DRD3DRD4DRD2CYP1A2 | |
| SCHEMBL31112405 | 0.77 | GAA (0.47) | OPRM1DRD3DRD4DRD2CYP1A2 | |
| SCHEMBL11611265 | 0.76 | CYP1A2 (0.50) | OPRM1DRD3DRD4DRD2CYP1A2 | |
| SCHEMBL8188868 | 0.74 | OPRM1 (0.41) | OPRM1DRD3DRD4DRD2CYP1A2 | |
| SCHEMBL1310699 | 0.72 | CYP1A2 (0.52) | OPRM1DRD3DRD4DRD2CYP1A2 | |
| SCHEMBL10445351 | 0.71 | HIF1A (0.46) | OPRM1DRD3DRD4DRD2CYP1A2 | |
| SCHEMBL8073736 | 0.70 | SMN1; SMN2 (0.53) | OPRM1DRD3DRD2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130478-A | Chlorination of lactones to improve stability to heat or light | SOCIETE NATIONALE DE POUDRES ET EXPLOSIFS (FR) | 1992-07-14 | — | — | US | disclosed |