Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 11/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726192 | 0.86 | CHRM4 (0.55) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL560935 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL4431781 | 0.80 | SIGMAR1 (0.66) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL9661051 | 0.80 | CYP2C9 (0.47) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL11602752 | 0.80 | KIF11 (0.54) | SMN1; SMN2KCNH2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL301346 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL117473 | 0.77 | CYP2C19 (0.43) | SMN1; SMN2LMNACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28986870 | 0.77 | KCNN4 (0.42) | SMN1; SMN2LMNABCL2KDM4EMAPK1 | |
| SCHEMBL11868000 | 0.77 | BCL2 (0.49) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL4862217 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020449-A1 | IMIDAZOLINE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |