Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944759 | 0.82 | POLB (0.54) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL11679195 | 0.79 | ELANE (0.41) | MAPT | |
| SCHEMBL25068493 | 0.79 | POLB (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL672151 | 0.78 | ALDH1A1 (0.43) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL15339017 | 0.77 | POLB (0.50) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL11175137 | 0.77 | THRB (0.42) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL9580207 | 0.77 | THRB (0.46) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL15500176 | 0.76 | ALDH1A1 (0.40) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL20364324 | 0.76 | POLB (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL14036917 | 0.76 | TDP1 (0.49) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171806-A | Phenylmaleimide, dially diphenate, bisphenol ester; lenses | NIPPON SHEET GLASS CO., LTD. (JP) | 1992-12-15 | — | — | US | disclosed |