SCHEMBL9719451

SCHEMBL9719451

Nc1cc(S(=O)(=O)c2ccccc2)c(Oc2ccccc2)c(Oc2ccccc2)c1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.49
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 3/20 0.42
GAA P10253 2/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
SOS1 Q07889 1/20 0.40
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP12 P39900 1/20 0.39
MMP13 P45452 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943509 0.92 CA1 (0.41) HTR6ALDH1A1KDM4EGAAHPGD
SCHEMBL1662788 0.83 HTR6 (0.50) HTR6ALDH1A1KDM4EGAAPKM
SCHEMBL9722495 0.79 HTR6 (0.45) HTR6ALDH1A1KDM4EGAAPKM
SCHEMBL7745328 0.78 HTR6 (0.61) HTR6ALDH1A1KDM4EGAAPKM
SCHEMBL459805 0.75 HTR6 (0.60) HTR6ALDH1A1KDM4EGAAPKM
SCHEMBL3272221 0.74 CA1 (0.42) HTR6KDM4EGAAHTTSMN1; SMN2
SCHEMBL30618213 0.74 CA1 (0.42) HTR6KDM4EGAAHTTSMN1; SMN2
SCHEMBL17774701 0.74 HTR6 (0.69) HTR6ALDH1A1KDM4EGAAPKM
SCHEMBL10342802 0.72 HTR6 (0.53) HTR6ALDH1A1KDM4EGAAPKM
SCHEMBL4464881 0.71 HTR6 (0.55) HTR6ALDH1A1KDM4EGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5081196-A Containing an acetylenically unsaturated monoamine compound UBE INDUSTRIES, LTD. (JP) 1992-01-14 US claimed
US-4963645-A UNSATURATED END GROUPS UBE INDUSTRIES, LTD. (JP) 1990-10-16 US claimed
US-4921745-A Honeycomb structure of aromatic polyimide UBE INDUSTRIES, LTD. (JP) 1990-05-01 US claimed
EP-0357367-A2 Terminal-modified aromatic imide oligomer composition UBE INDUSTRIES, LTD. (JP) 1990-03-07 EP claimed
EP-0304913-A2 Terminal-modified imide oligomer and solution composition of the same UBE INDUSTRIES, LTD. (JP) 1989-03-01 EP claimed
US-5147943-A Thermosetting resin; polyimide containing a modifying monoamine alcohol UBE INDUSTRIES, LTD. (JP) 1992-09-15 US disclosed
US-5081196-A Containing an acetylenically unsaturated monoamine compound UBE INDUSTRIES, LTD. (JP) 1992-01-14 US disclosed
US-4963645-A UNSATURATED END GROUPS UBE INDUSTRIES, LTD. (JP) 1990-10-16 US disclosed
EP-0379131-A2 Thermosetting resin composition UBE INDUSTRIES, LTD. (JP) 1990-07-25 EP disclosed
EP-0371154-A1 Prepreg of reinforced imide oligomer UBE INDUSTRIES, LTD. (JP) 1990-06-06 EP disclosed
US-4921745-A Honeycomb structure of aromatic polyimide UBE INDUSTRIES, LTD. (JP) 1990-05-01 US disclosed
EP-0357367-A2 Terminal-modified aromatic imide oligomer composition UBE INDUSTRIES, LTD. (JP) 1990-03-07 EP disclosed
EP-0304913-A2 Terminal-modified imide oligomer and solution composition of the same UBE INDUSTRIES, LTD. (JP) 1989-03-01 EP disclosed