SCHEMBL459805

SCHEMBL459805

Nc1cc(S(=O)(=O)c2ccccc2)c(N)c(N)c1N

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.60
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 3/20 0.47
GAA P10253 3/20 0.45
HPGD P15428 2/20 0.45
PKM P14618 1/20 0.45
POLB P06746 1/20 0.44
GFER P55789 1/20 0.44
NPY1R P25929 1/20 0.43
LMNA P02545 1/20 0.42
KMT2A Q03164 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
PLA2G7 Q13093 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17774701 0.84 HTR6 (0.69) HTR6ALDH1A1KDM4EGAAHPGD
SCHEMBL3291029 0.82 HTR6 (0.62) HTR6ALDH1A1KDM4EGAAHPGD
SCHEMBL3290542 0.81 GAA (0.42) HTR6ALDH1A1KDM4EGAAPKM
SCHEMBL4464881 0.80 HTR6 (0.55) HTR6ALDH1A1KDM4EGAAHPGD
SCHEMBL26294642 0.79 HTR6 (0.53) HTR6ALDH1A1KDM4EGAAHPGD
SCHEMBL6733413 0.78 HTR6 (0.51) HTR6ALDH1A1KDM4EGAAHPGD
SCHEMBL9337512 0.77 HTR6 (0.50) HTR6ALDH1A1KDM4EGAAHPGD
SCHEMBL11213674 0.76 MEN1 (0.55) HTR6ALDH1A1KDM4EHPGDPKM
SCHEMBL30751995 0.75 HTR6 (1.00) HTR6ALDH1A1KDM4EGAAHPGD
SCHEMBL395274 0.75 HTR6 (1.00) HTR6ALDH1A1KDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820314-B2 Proton-conducting membrane and use thereof BASF FUEL CELL RESEARCH GMBH (DE) 2010-10-26 US claimed
EP-1706442-B1 PROTON-CONDUCTING MEMBRANE AND USE THEREOF BASF FUEL CELL GMBH (DE) 2010-05-26 EP claimed
EP-1706442-A1 PROTON-CONDUCTING MEMBRANE AND USE THEREOF Pemeas GmbH (DE) 2006-10-04 EP claimed
WO-2005063852-A1 PROTON-CONDUCTING MEMBRANE AND USE THEREOF PEMEAS GMBH (DE) 2005-07-14 WO claimed
EP-1054031-A2 Increasing the molecular weight and modification of condensation polymers Ciba SC Holding AG (CH) 2000-11-22 EP claimed
EP-0119271-A4 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. STANFORD RES INST INT (US) 1985-07-01 EP claimed
EP-0119271-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. STANFORD RES INST INT (US) 1984-09-26 EP claimed
EP-0119192-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS SRI INTERNATIONAL (US) 1984-09-26 EP claimed
WO-1984001160-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS STANFORD RES INST INT (US) 1984-03-29 WO claimed
WO-1984001162-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS STANFORD RES INST INT (US) 1984-03-29 WO claimed
JP-54138189-A None JP disclosed
JP-60208329-A None JP disclosed
US-11613649-B2 Thermally-rearranged polymer blends for gas separation membranes BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-03-28 US disclosed
US-20210095122-A1 THERMALLY-REARRANGED POLYMER BLENDS FOR GAS SEPARATION MEMBRANES UNITED STATES DEPARTMENT OF ENERGY 2021-04-01 US disclosed
US-10188992-B2 Polybenzimidazoles and methods of making and using thereof BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-01-29 US disclosed
EP-0293091-A1 Poly(amide-benzazoles) MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-30 EP disclosed
EP-0247856-A2 Preparation of aromatic heterocyclic polymers THE DOW CHEMICAL COMPANY (US) 1987-12-02 EP disclosed
EP-0177182-A2 Two-stage process for producing polybenzimidazoles from dicarboxylic component CELANESE CORPORATION (US) 1986-04-09 EP disclosed
JP-S60208329-A POLYPHENYLQUINOXALINE RESIN HAVING IMPROVED MOLDABILITY AGENCY OF IND SCIENCE & TECHNOL 1985-10-19 JP disclosed
JP-S54138189-A SEPARATION AND PURIFICATION OF UROKINASE TAKEDA CHEM IND LTD 1979-10-26 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10188992-B2 Polybenzimidazoles and methods of making and using thereof PHB2, SI, NISCH HTR6 15/4885ALDH1A1 3432/4885KDM4E 473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.