Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666735 | 0.84 | SLC6A2 (0.50) | SLC6A2TAAR1SMN1; SMN2HIF1ALMNA | |
| SCHEMBL6093963 | 0.84 | SLC6A2 (0.50) | SLC6A2TAAR1SMN1; SMN2HIF1ALMNA | |
| SCHEMBL7284495 | 0.76 | PPARG (0.54) | SLC6A2TAAR1SMN1; SMN2HIF1ALMNA | |
| SCHEMBL17844847 | 0.76 | CA12 (0.43) | SLC6A2TAAR1SMN1; SMN2HIF1AMMP1 | |
| SCHEMBL9150107 | 0.75 | SLC6A2 (0.61) | SLC6A2TAAR1SMN1; SMN2HIF1ALMNA | |
| SCHEMBL18605874 | 0.75 | SLC6A2 (0.61) | SLC6A2TAAR1SMN1; SMN2HIF1ALMNA | |
| Phentermine SCHEMBL28815884 | 0.74 | SLC6A2 (0.73) | SLC6A2TAAR1SMN1; SMN2HIF1ALMNA | |
| Hydrochloric Acid SCHEMBL7288001 | 0.73 | SLC6A2 (0.53) | SLC6A2TAAR1SMN1; SMN2HIF1ALMNA | |
| Phentermine SCHEMBL28338903 | 0.72 | SLC6A2 (0.76) | SLC6A2TAAR1SMN1; SMN2HIF1ALMNA | |
| Hydrochloric Acid SCHEMBL7293805 | 0.72 | SLC6A2 (0.57) | SLC6A2TAAR1SMN1; SMN2HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009669-A1 | ABUSE-RESISTANT AMPHETAMINE PRODRUGS | SHIRE LLC (US) | 2011-01-13 | — | — | US | disclosed |
| US-7659253-B2 | Abuse-resistant amphetamine prodrugs | SHIRE LLC (US) | 2010-02-09 | — | — | US | disclosed |
| US-20090234002-A1 | ABUSE-RESISTANT AMPHETAMINE PRODRUGS | SHIRE LLC (US) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234002-A1 | ABUSE-RESISTANT AMPHETAMINE PRODRUGS | COMT, CYP3A5, CYP2D6 | SLC6A2 7/4885TAAR1 161/4885SMN1; SMN2 568/4885 |
| US-20110009669-A1 | ABUSE-RESISTANT AMPHETAMINE PRODRUGS | COMT, CYP3A5, CYP2D6 | SLC6A2 7/4885TAAR1 161/4885SMN1; SMN2 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.