Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505374 | 0.93 | TSHR (0.52) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL10626508 | 0.92 | TSHR (0.41) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL27556372 | 0.84 | KDM4E (0.41) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL522412 | 0.84 | TSHR (0.53) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL522175 | 0.81 | TSHR (0.61) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL27971417 | 0.80 | TSHR (0.45) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL1719721 | 0.79 | TSHR (0.59) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL31386837 | 0.78 | MAPT (0.40) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL19478152 | 0.78 | TSHR (0.42) | TSHRMAPK1KDM4EALDH1A1KMT2A | |
| SCHEMBL31386749 | 0.78 | MAPT (0.40) | TSHRMAPK1MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281266-B1 | 3-AMINO-2,4,5-TRIFLUOROBENZOIC ACID AND ITS MANUFACTURE | NIPPON SHOKUBAI CO., LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4782179-A | 3-amino-2,4,5-trifluorobenzoic acid and a method for manufacture thereof | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0281266-A1 | 3-Amino-2,4,5-trifluorobenzoic acid and its manufacture | NIPPON SHOKUBAI CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |