Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719721 | 0.94 | TSHR (0.59) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL7198377 | 0.92 | TSHR (0.57) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL522175 | 0.92 | TSHR (0.61) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL8652422 | 0.91 | TSHR (0.47) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL8350876 | 0.87 | TSHR (0.48) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL16300563 | 0.85 | TSHR (0.47) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL17465159 | 0.85 | TSHR (0.43) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL24436896 | 0.84 | TSHR (0.50) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL9719599 | 0.84 | TSHR (0.46) | TSHRMAPK1MAPTCA12CA1 | |
| SCHEMBL8593844 | 0.84 | TSHR (0.46) | TSHRMAPK1MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856557-A | Process for producing hexafluorobiphenyl -3,3',4,4'-Tetracarboxylic acid precursors | UBE INDUSTRIES, LTD. (JP) | 1999-01-05 | — | — | US | claimed |
| JP-4334363-A | — | — | None | — | — | JP | disclosed |
| CN-106380729-B | Novel PVC heat stabilizer | 邵卫东 | 2019-01-29 | — | — | CN | disclosed |
| CN-106380729-A | Novel PVC heat stablizer | 邵卫东 | 2017-02-08 | — | — | CN | disclosed |
| EP-3046176-A1 | NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY INCLUDING SAME | LG Chem, Ltd. (KR) | 2016-07-20 | — | — | EP | disclosed |
| EP-2415741-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120029195-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120010417-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |
| EP-1304329-B1 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI SANKYO CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-0807630-B1 | HETEROCYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-5488152-A | Process for the preparation of 4-alkoxy-3,5,6-trifluoro-phthalic acids and 3-alkoxy-2,4,5-trifluorobenzoic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-30 | — | — | US | disclosed |
| EP-0667334-A2 | Process for the preparation of 4-alkoxy-3,5,6-trifluorophthalic acids and 3-alkoxy-2,4,5-trifluorobenzoic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-16 | — | — | EP | disclosed |
| US-5286723-A | Spiro compound | DAIICHI SEIYAKU CO., LTD. | 1994-02-15 | — | — | US | disclosed |
| EP-0357047-B1 | Spiro compounds | DAIICHI SEIYAKU CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| EP-0529688-A2 | Azaspiro n,m alkanes and diazaspiro n,m -alkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| JP-H04334363-A | BIS(3,4-DICARBOXY-2,5,6-TRIFLUOROPHENYL)SULFIDE-TETRAMETHYLESTER AND PRODUCTION THEREOF | HITACHI CHEM CO LTD | 1992-11-20 | — | — | JP | disclosed |
| EP-0218111-B1 | PROCESS FOR THE PREPARATION OF TETRAFLUOROBENZOIC ACID | WARNER LAMBERT CO (US) | 1990-07-25 | — | — | EP | disclosed |
| EP-0357047-A1 | Spiro compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4782180-A | CATALYTIC DECARBOXYLATION OF TETRAFLUOROPHTHALTIC ACID | WARNER-LAMBERT COMPANY (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0218111-A1 | Process for the preparation of tetrafluorobenzoic acid | WARNER-LAMBERT COMPANY (US) | 1987-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010417-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | ADH1A, ADH1C, ADH5 | TSHR 2221/4885MAPK1 3196/4885MAPT 1818/4885 |
| US-20120029195-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | ADH1A, ADH1C, ADH5 | TSHR 2411/4885MAPK1 2681/4885MAPT 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.