Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719687 | 0.69 | GRIN2B (0.44) | GRIN2BSLC6A2 | |
| SCHEMBL9719713 | 0.69 | ADRB2 (0.38) | MAPK1SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL9145085 | 0.61 | ADRB2 (0.39) | MAPK1SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL11641507 | 0.61 | TSHR (0.42) | KDM1ARCOR1OPRM1OPRD1OPRK1 | |
| SCHEMBL18682149 | 0.58 | IDO1 (0.54) | OPRM1MAPK1CHRM1SLC6A2SLC6A4 | |
| SCHEMBL15338275 | 0.58 | IDO1 (0.54) | OPRM1MAPK1CHRM1SLC6A2SLC6A4 | |
| SCHEMBL686394 | 0.58 | IDO1 (0.54) | OPRM1MAPK1CHRM1SLC6A2SLC6A4 | |
| SCHEMBL17529748 | 0.57 | CYP2D6 (0.39) | OPRM1OPRD1OPRK1OPRL1ADRA2A | |
| SCHEMBL17802339 | 0.57 | CHRM1 (0.50) | CHRM1SLC6A2SLC6A4DRD3CHRM2 | |
| SCHEMBL17802337 | 0.57 | CHRM1 (0.50) | CHRM1SLC6A2SLC6A4DRD3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079374-A | Cyclopropyl-oxirane compounds as intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-07 | — | — | US | disclosed |
| US-4983208-A | Plant diseases, cereal crops | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |
| EP-0298332-B1 | HYDROXY-ALKYLAZOLYL DERIVATIVES | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |
| US-4925482-A | Fungicidal and plant growth-regulating hydroxyalkyl-azolyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| US-4925865-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |