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SCHEMBL9719919

SCHEMBL9719919

O=C(O)c1ccc(Oc2ccc(C(c3ccccc3)(c3ccc(Oc4ccc(C(=O)O)cc4)cc3)C(F)(F)F)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SRD5A2 P31213 5/20 0.57
▸ PARP10 Q53GL7 2/20 0.50
▸ PARP15 Q460N3 1/20 0.50
▸ MAPK14 Q16539 2/20 0.48
▸ FAAH O00519 1/20 0.48
▸ EPHX2 P34913 1/20 0.48
▸ NR4A2 P43354 1/20 0.46
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ PKM P14618 1/20 0.45
▸ AKR1C3 P42330 1/20 0.45
▸ NR1H4 Q96RI1 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ POLB P06746 2/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL765966 0.90 SRD5A2 (0.55) SRD5A2EPHX2TSHRHPGD
SCHEMBL10558699 0.90 SRD5A2 (0.55) SRD5A2EPHX2TSHRHPGD
SCHEMBL8624817 0.88 MAPT (0.58) SRD5A2PARP10MAPK14MEN1KMT2A
SCHEMBL11358491 0.84 LTA4H (0.50) MAPK14EPHX2MEN1KMT2AALDH1A1
SCHEMBL11358313 0.84 SRD5A2 (0.61) SRD5A2EPHX2MEN1KMT2AALDH1A1
SCHEMBL6351953 0.83 SRD5A2 (0.65) SRD5A2PARP10PARP15NR4A2PKM
SCHEMBL8657209 0.82 POLB (0.58) MAPK14MEN1KMT2AAKR1C3ALDH1A1
SCHEMBL29404749 0.82 POLB (0.58) MAPK14MEN1KMT2AAKR1C3ALDH1A1
SCHEMBL21656465 0.81 PARP15 (0.55) SRD5A2PARP10PARP15MAPK14FAAH
SCHEMBL21656834 0.81 PARP15 (0.55) SRD5A2PARP10PARP15MAPK14FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0317944-A2 Polymers prepared from 4,4'-bis-(2-(amino (halo) phenoxyphenyl) hexafluoroisopropyl) diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-05-31 — — EP claimed
US-5109107-A Excellent flow properties and hydrolytic stability HOECHT CELANESE CORP. (US) 1992-04-28 — — US disclosed
US-5037949-A Fluorine containing polyamides, polyimides HOECHST CELANESE CORP. (US) 1991-08-06 — — US disclosed
US-4978734-A HEAT AND SOLVENT RESISTANT, PROCESSABLE; FILMS HOECHST CELANESE CORP. (US) 1990-12-18 — — US disclosed
EP-0397024-A1 Polyamide polymers having 12-f fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-11-14 — — EP disclosed
EP-0397022-A2 Polyimide-Polyamide polymers having fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-11-14 — — EP disclosed
US-4962181-A FROM AROMATIC ETHER-CONTAINING DIAMINES; HEAT RESISTANCE, STABILITY, STRENGTH, WORKABILITY; FOR FILMS HOECHST CELANESE CORP. (US) 1990-10-09 — — US disclosed
US-4962183-A HEAT, OXIDATION AND SOLVENT RESISTANCE; MOLDING MATERIALS; MELT PROCESSIBILITY; FIBERS, FILMS AND SHEETS HOECHST CELANESE CORP. (US) 1990-10-09 — — US disclosed
EP-0387061-A2 Novel polyamide-polyamide and polybenzoxazole-polyamide polymers HOECHST CELANESE CORPORATION (US) 1990-09-12 — — EP disclosed
US-4925915-A FLUORINE CONTAINING POLYIMIDES HOECHST CELANESE CORP. (US) 1990-05-15 — — US disclosed
EP-0317944-A2 Polymers prepared from 4,4'-bis-(2-(amino (halo) phenoxyphenyl) hexafluoroisopropyl) diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-05-31 — — EP disclosed