Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | FOS | P01100 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19190027 | 0.84 | TAAR1 (0.63) | ADRB2CALM1HTR1ATAAR1TSHR | |
| SCHEMBL8294109 | 0.84 | TAAR1 (0.67) | ADRB2HTR1ATAAR1TSHRMAPK1 | |
| SCHEMBL27779364 | 0.82 | CYP3A4 (0.63) | ADRB2CALM1HTR1ATAAR1TSHR | |
| SCHEMBL5072123 | 0.81 | TAAR1 (0.76) | ADRB2CALM1TAAR1TSHRMAPK1 | |
| SCHEMBL9578088 | 0.81 | ALOX5 (0.53) | ADRB2HTR1ATSHRCYP1A2CYP3A4 | |
| SCHEMBL9281549 | 0.78 | TAAR1 (0.76) | CALM1TAAR1TSHRMAPK1FOS | |
| SCHEMBL10628702 | 0.78 | KMT2A (0.47) | ADRB2TSHRHSD17B2CYP1A2CYP3A4 | |
| SCHEMBL27940007 | 0.75 | HTR1A (0.82) | ADRB2CALM1HTR1ATAAR1TSHR | |
| SCHEMBL17780116 | 0.74 | PTPN1 (0.82) | ADRB2CALM1TAAR1TSHRMAPK1 | |
| SCHEMBL29604390 | 0.74 | PTPN1 (0.82) | ADRB2CALM1TAAR1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106871-A | Reduced side effects | TSUMURA & CO. (JP) | 1992-04-21 | — | — | US | disclosed |