⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19147467 | 0.74 | — | — | |
| SCHEMBL22081976 | 0.74 | — | — | |
| SCHEMBL991580 | 0.72 | — | — | |
| SCHEMBL22312277 | 0.69 | — | — | |
| SCHEMBL15587649 | 0.67 | — | — | |
| SCHEMBL11448691 | 0.65 | — | — | |
| SCHEMBL26000434 | 0.64 | LMNA (0.31) | — | |
| SCHEMBL22311788 | 0.62 | — | — | |
| SCHEMBL22312578 | 0.62 | — | — | |
| Methane SCHEMBL9512530 | 0.62 | CA1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904511-B1 | HOMOGEMCITABINES | PHARMACON FORSCHUNG & BERATUNG GMBH (AT) | 2009-07-08 | — | — | EP | claimed |
| US-20080249119-A1 | Nucleosiding a protected cytosine with a protected hexose, deprotecting to obtain gemcitabine; administering as produgs; cancers of the lungs, ovaries, pancreas and bladder; cost efficiency; simplification | PHARMACON-FORSCHUNG UND BERATUNG GMBH (AT) | 2008-10-09 | — | — | US | claimed |
| EP-0194972-A2 | Novel cyclosporins | SANDOZ AG (CH) | 1986-09-17 | — | — | EP | claimed |
| US-12570631-B2 | Substituted N-(4-(pyrimidin and pyridin-4-yl)benzylcarboxamides and its use for treating disorders responsive to inhibition of Btk | BIOGEN MA INC. (US) | 2026-03-10 | — | — | US | disclosed |
| EP-4051680-B1 | CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC (US) | 2025-09-03 | — | — | EP | disclosed |
| US-12391697-B2 | Condensed bi-heterocycles as inhibiting agents for Bruton's tyrosine kinase | BIOGEN MA INC. (US) | 2025-08-19 | — | — | US | disclosed |
| US-20240327380-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2024-10-03 | — | — | US | disclosed |
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| US-20230121818-A1 | BTK INHIBITORS | BIOGEN MA INC. | 2023-04-20 | — | — | US | disclosed |
| US-20230025892-A1 | CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC. | 2023-01-26 | — | — | US | disclosed |
| WO-2009143049-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND USE THEREOF AS GPR119 MODULATORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009109549-A1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009055331-A2 | BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS MODULATORS OF THE ACTIVITY OF GPR119 | SCHERING CORPORATION (US) | 2009-04-30 | — | — | WO | disclosed |
| US-20080249119-A1 | Nucleosiding a protected cytosine with a protected hexose, deprotecting to obtain gemcitabine; administering as produgs; cancers of the lungs, ovaries, pancreas and bladder; cost efficiency; simplification | PHARMACON-FORSCHUNG UND BERATUNG GMBH (AT) | 2008-10-09 | — | — | US | disclosed |
| US-6974658-B2 | HIGH MOLECULAR COMPOUND, MONOMER COMPOUNDS AND PHOTOSENSITIVE COMPOSITION FOR PHOTORESIST, PATTERN FORMING METHOD UTILIZING PHOTOSENSITIVE COMPOSITION, AND METHOD OF MANUFACTURING ELECTRONIC COMPONENTS | KABUSHIKI KAISHA TOSHIBA (JP) | 2005-12-13 | — | — | US | disclosed |
| US-20030235781-A1 | High molecular compound, monomer compounds and photosensitive composition for photoresist, pattern forming method utilizing photosensitive composition, and method of manufacturing electronic components | KABUSHIKI KAISHA TOSHIBA (JP) | 2003-12-25 | — | — | US | disclosed |
| EP-0194972-B1 | NOVEL CYCLOSPORINS | SANDOZ AG (CH) | 1992-07-29 | — | — | EP | disclosed |
| US-4771122-A | IMMUNOSUPPRESIVE, ANTIPARASITIC, ANTIINFLAMMATORY | SANDOZ LTD. (CH) | 1988-09-13 | — | — | US | disclosed |
| EP-0194972-A2 | Novel cyclosporins | SANDOZ AG (CH) | 1986-09-17 | — | — | EP | disclosed |