Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969725 | 0.89 | MAPT (0.54) | MAPTALDH1A1HSD17B10RAB9AMEN1 | |
| SCHEMBL17795639 | 0.88 | MAPT (0.52) | MAPTALDH1A1HSD17B10RAB9AMEN1 | |
| SCHEMBL21094226 | 0.88 | CYP3A4 (0.45) | MAPTALDH1A1HSD17B10RAB9AMEN1 | |
| SCHEMBL16479585 | 0.86 | CASP3 (0.54) | MAPTALDH1A1HSD17B10RAB9AMEN1 | |
| SCHEMBL9617079 | 0.85 | RARB (0.57) | MAPTALDH1A1HSD17B10RAB9AMEN1 | |
| SCHEMBL8651956 | 0.85 | MAPT (0.47) | MAPTALDH1A1HSD17B10RAB9AMEN1 | |
| SCHEMBL8970306 | 0.84 | CYP2D6 (0.56) | ALDH1A1HSD17B10RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7883759 | 0.83 | NR5A1 (0.56) | MAPTALDH1A1HSD17B10RAB9AMEN1 | |
| SCHEMBL9158713 | 0.83 | MAPT (0.48) | MAPTALDH1A1HSD17B10RAB9AMEN1 | |
| SCHEMBL5848362 | 0.81 | CYP3A4 (0.48) | MAPTALDH1A1HSD17B10RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338054-B1 | CROSS COUPLING OF TITANIUM ORGANYLS | MERCK PATENT GmbH (DE) | 1992-12-30 | — | — | EP | disclosed |
| WO-1989003812-A1 | CROSS COUPLING OF TITANIUM ORGANYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-05-05 | — | — | WO | disclosed |