Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764112 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL2928727 | 0.94 | TSHR (0.54) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL29176807 | 0.94 | TSHR (0.54) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL1502178 | 0.93 | TSHR (0.52) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL2172519 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL15862378 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL29176805 | 0.84 | KMT2A (0.53) | ALDH1A1TSHRTDP1PTPN11CA1 | |
| SCHEMBL15862295 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL8208740 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL16435165 | 0.81 | TSHR (0.37) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155274-A | Catalyst for amination of unsaturated compounds with secondary amine | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-13 | — | — | US | disclosed |
| US-5057618-A | Catalysts | HOECHST AKTIENGESELLSCHAFT (JP) | 1991-10-15 | — | — | US | disclosed |
| US-RE31812-E | TO ALDEHYDES IN PRESENCE OF CATALYTIC SYSTEM CONTAINING RHODIUM AND SULFONATED ARYL PHOSPHINE COMPOUND | RHONE-POULENC INDUSTRIES (FR) | 1985-01-22 | — | — | US | disclosed |
| US-4260750-A | OF DIENES, TRIARYLPHOSPHINE CATALYST | RHONE-POULENC INDUSTRIES (FR) | 1981-04-07 | — | — | US | disclosed |
| US-4248802-A | Catalytic hydroformylation of olefins | RHONE-POULENC INDUSTRIES (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4219677-A | FOR DIENES IN PRESENCE OF SULFONATED PHOSPHINE CATALYST | RHONE-POULENC INDUSTRIES (FR) | 1980-08-26 | — | — | US | disclosed |
| US-4142060-A | DIENES, WATER | RHONE-POULENC INDUSTRIES (FR) | 1979-02-27 | — | — | US | disclosed |
| US-4087452-A | Process of hydrocyanation of unsaturated organic compounds containing at least one ethylenic double bond | RHONE-POULENC INDUSTRIES (FR) | 1978-05-02 | — | — | US | disclosed |