SCHEMBL2928727

SCHEMBL2928727

O=P(c1ccccc1)(c1ccccc1)c1cccc(S(=O)(=O)O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ SNCA P37840 1/20 0.47
▸ CASP6 P55212 2/20 0.44
▸ POLB P06746 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ APOBEC3A P31941 1/20 0.44
▸ CTDSP1 Q9GZU7 1/20 0.44
▸ APOBEC3G Q9HC16 1/20 0.44
▸ DUSP3 P51452 2/20 0.41
▸ PTPN5 P54829 2/20 0.41
▸ PTPN11 Q06124 2/20 0.41
▸ NSD2 O96028 1/20 0.41
▸ CASP7 P55210 1/20 0.41
▸ APEX1 P27695 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29176807 1.00 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL1502178 0.98 TSHR (0.52) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL9720123 0.94 ALDH1A1 (0.53) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL30764112 0.94 ALDH1A1 (0.53) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL30764109 0.85 KMT2A (0.49) TSHRALDH1A1KMT2APTPN11CA2
SCHEMBL15698201 0.85 HTR6 (0.50) TSHRSMN1; SMN2ALDH1A1CASP6POLB
SCHEMBL2172519 0.81 ALDH1A1 (0.52) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL15862378 0.80 ALDH1A1 (0.41) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL1502176 0.80 KMT2A (0.62) ALDH1A1TDP1CASP6POLBKMT2A
Triphenylphosphine Oxide SCHEMBL8328973 0.80 CA2 (0.52) TSHRSMN1; SMN2ALDH1A1TDP1CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4222141-B1 LOW REACTIVITY HYDROCARBON DISPERSING AGENTS IN THE AQUEOUS POLYMERIZATION OF FLUOROPOLYMERS CHEMOURS CO FC LLC (US) 2025-08-06 — — EP disclosed
US-20240002553-A1 EMPLOYING LOW REACTIVITY HYDROCARBON DISPERSING AGENT IN AQUEOUS POLYMERIZATION OF FLUOROPOLYMERS THE CHEMOURS COMPANY FC, LLC (US) 2024-01-04 — — US disclosed
EP-4222141-A1 LOW REACTIVITY HYDROCARBON DISPERSING AGENTS IN THE AQUEOUS POLYMERIZATION OF FLUOROPOLYMERS The Chemours Company FC, LLC (US) 2023-08-09 — — EP disclosed
EP-2231682-B1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE THEREOF IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES LLC (US) 2016-01-06 — — EP disclosed
US-8394978-B2 Sulfonated organophosphine compounds and use thereof in hydroformylation processes DOW GLOBAL TECHNOLOGIES LLC (US) 2013-03-12 — — US disclosed
US-20110263879-A1 ZWITTERIONIC PHOSPHONIUM SALTS THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 2011-10-27 — — US disclosed
EP-2231682-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE THEREOF IN HYDROFORMYLATION PROCESSES Dow Global Technologies Inc. (US) 2010-09-29 — — EP disclosed
US-7618546-B1 Iron catalysis in oxidation by ozone IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2009-11-17 — — US disclosed
WO-2009091671-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE THEREOF IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES INC. (US) 2009-07-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002553-A1 EMPLOYING LOW REACTIVITY HYDROCARBON DISPERSING AGENT IN AQUEOUS POLYMERIZATION OF FLUOROPOLYMERS FPR1, NAF1, SIGMAR1 TSHR 2150/4885SMN1; SMN2 3046/4885ALDH1A1 2481/4885
US-20110263879-A1 ZWITTERIONIC PHOSPHONIUM SALTS CX3CR1, PHOSPHO1, CBR3 TSHR 3617/4885SMN1; SMN2 3972/4885ALDH1A1 785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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