Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.37 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31229949 | 0.88 | MEN1 (0.61) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL29640487 | 0.88 | MEN1 (0.61) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9720207 | 0.86 | MEN1 (0.42) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9720173 | 0.84 | HTT (0.49) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL3501786 | 0.84 | MEN1 (0.58) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL29521479 | 0.84 | MEN1 (0.58) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL1626655 | 0.83 | MEN1 (0.62) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL1628205 | 0.83 | MEN1 (0.62) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL5143693 | 0.83 | MEN1 (0.62) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL1626703 | 0.83 | MEN1 (0.62) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |