Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441375 | 0.84 | USP2 (0.54) | TDP1L3MBTL1USP2HTTLPAR5 | |
| SCHEMBL9720258 | 0.83 | TDP1 (0.55) | TDP1L3MBTL1LMNAHRH1TBXAS1 | |
| SCHEMBL23015074 | 0.82 | TDP1 (0.68) | TDP1L3MBTL1HRH1TBXAS1TRPV1 | |
| SCHEMBL10061567 | 0.81 | L3MBTL1 (0.75) | TDP1L3MBTL1HRH1TBXAS1TRPV1 | |
| SCHEMBL2098501 | 0.80 | TDP1 (0.55) | TDP1L3MBTL1HRH1TBXAS1CYP2A6 | |
| SCHEMBL2608878 | 0.79 | TDP1 (0.54) | TDP1L3MBTL1HRH1TBXAS1CYP2A6 | |
| SCHEMBL25382598 | 0.79 | TDP1 (0.96) | TDP1L3MBTL1HRH1TBXAS1TRPV1 | |
| SCHEMBL6114977 | 0.79 | TDP1 (0.96) | TDP1L3MBTL1HRH1TBXAS1TRPV1 | |
| SCHEMBL25380936 | 0.79 | TDP1 (0.96) | TDP1L3MBTL1HRH1TBXAS1TRPV1 | |
| SCHEMBL6114843 | 0.79 | TDP1 (0.96) | TDP1L3MBTL1HRH1TBXAS1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |