SCHEMBL9720284

SCHEMBL9720284

CNC(=O)OC(C)(C)OC(=O)NC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.38
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CYP2D6 P10635 1/20 0.34
CHRM1 P11229 1/20 0.34
NFKB1 P19838 1/20 0.34
CHRM3 P20309 1/20 0.34
MAPK1 P28482 1/20 0.34
CHRNA7 P36544 1/20 0.34
DGAT1 O75907 1/20 0.33
LMNA P02545 1/20 0.33
APEX1 P27695 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15116333 0.90 GAA (0.38) TDP1ALDH1A1TSHRHSD17B10CHRNB2
SCHEMBL21887128 0.84 CHRNB2 (0.35) TDP1ALDH1A1TSHRHSD17B10CHRNB2
SCHEMBL303868 0.82
SCHEMBL30402270 0.80 DGAT1 (0.42) TDP1NFKB1DGAT1
Hydrochloric Acid SCHEMBL27497408 0.80 DGAT1 (0.42) TDP1NFKB1DGAT1
SCHEMBL28175005 0.80
SCHEMBL21614030 0.78
SCHEMBL28262150 0.78
Propane SCHEMBL28996705 0.76 CA1 (0.44) TDP1ALDH1A1CYP2D6DGAT1EPHX1
SCHEMBL15512903 0.76 TDP1 (0.39) TDP1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5126476-A Reaction of aromatic compound with alkylenebis(alkyl carbamate) in presence of acid catalyst and polar aprotic solv ent ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1992-06-30 US disclosed