SCHEMBL9720338

SCHEMBL9720338

Cc1cc(Oc2ccc(Cl)cc2Cl)c(C)c(Cl)c1NC(=O)NC(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.42
ATM Q13315 1/20 0.42
MAPT P10636 3/20 0.40
ALDH1A1 P00352 1/20 0.40
ALOX12 P18054 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
PYGL P06737 4/20 0.39
STK39 Q9UEW8 1/20 0.39
PNLIP P16233 1/20 0.39
GHSR Q92847 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
MRGPRX4 Q96LA9 1/20 0.37
POLB P06746 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8659421 0.93 ATM (0.43) GCGRATMMAPTALDH1A1ALOX12
SCHEMBL8656588 0.92 GCGR (0.42) GCGRATMMAPTALDH1A1ALOX12
SCHEMBL8658202 0.91 MEN1 (0.47) GCGRATMMAPTALDH1A1ALOX12
SCHEMBL8665614 0.89 GCGR (0.56) GCGRATMMAPTALDH1A1NPSR1
SCHEMBL8660976 0.85 MAPT (0.40) GCGRATMMAPTALDH1A1ALOX12
SCHEMBL9135305 0.84 PNLIP (0.49) GCGRATMMAPTALDH1A1SMN1; SMN2
SCHEMBL8662516 0.84 KMT2A (0.45) GCGRATMMAPTALDH1A1ALOX12
SCHEMBL10752405 0.84 MEN1 (0.47) GCGRATMMAPTALDH1A1ALOX12
SCHEMBL8662538 0.83 MAPT (0.41) GCGRATMMAPTPYGLGHSR
SCHEMBL8660726 0.83 MEN1 (0.47) GCGRATMMAPTALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5135953-A Oral or injections; cattle, swine, poultry CIBA-GEIGY (US) 1992-08-04 US disclosed