SCHEMBL9720377

SCHEMBL9720377

C=CC(=O)OCOC(=O)c1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.41
THRB P10828 1/20 0.41
ALDH1A1 P00352 8/20 0.40
TSHR P16473 4/20 0.37
HSD17B10 Q99714 2/20 0.37
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
KDM4E B2RXH2 3/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.33
PBRM1 Q86U86 1/20 0.33
KMT2A Q03164 1/20 0.33
PTK2B Q14289 1/20 0.33
GSTO1 P78417 1/20 0.33
FOLH1 Q04609 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19210181 0.88 THRB (0.51) CYP3A4THRBALDH1A1TSHRHSD17B10
SCHEMBL29124873 0.86 ALDH1A1 (0.54) CYP3A4THRBALDH1A1TSHRHSD17B10
SCHEMBL28827207 0.86 CYP3A4 (0.38) CYP3A4THRBALDH1A1TSHRHSD17B10
SCHEMBL29402176 0.86 TSHR (0.49) CYP3A4THRBALDH1A1TSHRHSD17B10
SCHEMBL30408129 0.85 ALDH1A1 (0.51) CYP3A4THRBALDH1A1TSHRHSD17B10
SCHEMBL29399722 0.85 TSHR (0.51) CYP3A4THRBALDH1A1TSHRHSD17B10
SCHEMBL29399111 0.85 TSHR (0.51) CYP3A4THRBALDH1A1TSHRHSD17B10
SCHEMBL29399736 0.85 TSHR (0.51) CYP3A4THRBALDH1A1TSHRHSD17B10
SCHEMBL29124872 0.82 CYP3A4 (0.59) CYP3A4THRBALDH1A1TSHRHSD17B10
SCHEMBL28431291 0.80 CYP3A4 (0.67) CYP3A4ALDH1A1TSHRHSD17B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5122061-A Two part composition of acrylate or methacrylate monomers, trialkylboron or oxide thereof; for dental composite resin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-06-16 US disclosed