Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | ESRRA | P11474 | 4/20 | 0.52 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657630 | 0.90 | POLB (0.47) | SMN1; SMN2MAPTNPC1RAB9AHPGD | |
| SCHEMBL8674230 | 0.88 | KIT (0.47) | SMN1; SMN2MAPTNPC1RAB9AHPGD | |
| SCHEMBL5824966 | 0.88 | KDR (0.62) | METKDRKITPDGFRA | |
| SCHEMBL8656131 | 0.85 | ESRRA (0.51) | SMN1; SMN2MAPTNPC1RAB9AHPGD | |
| SCHEMBL9134978 | 0.82 | POLB (0.47) | SMN1; SMN2MAPTNPC1RAB9AHPGD | |
| SCHEMBL8660852 | 0.82 | ESRRA (0.48) | MAPTALDH1A1ESRRALMNAPOLB | |
| SCHEMBL8659697 | 0.82 | ESRRA (0.61) | SMN1; SMN2MAPTNPC1RAB9AHPGD | |
| SCHEMBL10961870 | 0.80 | RAB9A (0.49) | SMN1; SMN2MAPTNPC1RAB9AHPGD | |
| SCHEMBL8658892 | 0.80 | ESRRA (0.46) | SMN1; SMN2MAPTHPGDALDH1A1ALOX12 | |
| SCHEMBL5825282 | 0.80 | PDGFRA (0.71) | SMN1; SMN2MAPTNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |