Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888914 | 0.89 | TSHR (0.45) | TSHRALDH1A1MAPK1ESR1HSD17B10 | |
| SCHEMBL22129210 | 0.81 | TSHR (0.38) | TSHRALDH1A1MAPK1ESR1HSD17B10 | |
| SCHEMBL505263 | 0.78 | TSHR (0.52) | TSHRALDH1A1MAPK1ESR1HSD17B10 | |
| SCHEMBL9853251 | 0.76 | ALDH1A1 (0.47) | TSHRALDH1A1MAPK1ESR1 | |
| SCHEMBL776289 | 0.71 | CES2 (0.40) | TSHRALDH1A1MAPK1ESR1HSD17B10 | |
| SCHEMBL5532399 | 0.71 | ESR1 (0.34) | TSHRALDH1A1MAPK1ESR1TDP1 | |
| SCHEMBL14393316 | 0.70 | TDP1 (0.44) | TSHRMAPK1ESR1HSD17B10TDP1 | |
| SCHEMBL7530353 | 0.69 | PTPN1 (0.50) | TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL505527 | 0.67 | MEN1 (0.33) | TSHRMAPK1 | |
| SCHEMBL9320500 | 0.67 | CES2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169853-A | Antibacterial agents; administering to mammals for infection | STERLING DRUG INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5075319-A | Bactericides | STERLING DRUG INC. (US) | 1991-12-24 | — | — | US | disclosed |