SCHEMBL9720709

SCHEMBL9720709

COc1ccccc1N1CCN(Cc2ccccc2O)CC1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.71
HTR7 P34969 5/20 0.71
KMT2A Q03164 3/20 0.71
ALDH1A1 P00352 1/20 0.71
LMNA P02545 3/20 0.69
HTT P42858 3/20 0.69
TDP1 Q9NUW8 1/20 0.69
GAA P10253 1/20 0.68
DRD2 P14416 2/20 0.67
DRD4 P21917 2/20 0.67
HRH1 P35367 2/20 0.67
DRD3 P35462 2/20 0.67
HRH2 P25021 1/20 0.67
TSHR P16473 2/20 0.66
MEN1 O00255 1/20 0.66
MAPT P10636 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
ALOX15 P16050 1/20 0.66
HSD17B10 Q99714 1/20 0.66
ALOX12 P18054 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6131856 0.89 KDM4E (0.67) KDM4EHTR7KMT2AALDH1A1LMNA
SCHEMBL15937713 0.83 HTR7 (1.00) KDM4EHTR7KMT2AALDH1A1LMNA
SCHEMBL6131822 0.82 KDM4E (0.74) KDM4EHTR7KMT2AALDH1A1LMNA
SCHEMBL6131833 0.82 KDM4E (0.71) KDM4EHTR7KMT2AALDH1A1LMNA
SCHEMBL6131779 0.82 KDM4E (0.64) KDM4EHTR7KMT2AALDH1A1LMNA
SCHEMBL9720762 0.82 HTR7 (0.82) KDM4EHTR7KMT2AALDH1A1LMNA
SCHEMBL29764232 0.81 HTR7 (1.00) KDM4EHTR7KMT2AALDH1A1DRD2
SCHEMBL15937769 0.81 HTR7 (1.00) KDM4EHTR7KMT2AALDH1A1DRD2
SCHEMBL10796187 0.81 KDM4E (0.64) KDM4EHTR7KMT2AALDH1A1LMNA
SCHEMBL9720681 0.81 MAPK1 (0.78) KDM4EHTR7KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142052-A Cationic effect-driven carbinol/amine reaction LABORATOIRES SYNTEX (FR) 1992-08-25 US disclosed