Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.82 |
| ▸ | DRD2 | P14416 | 5/20 | 0.80 |
| ▸ | DRD4 | P21917 | 5/20 | 0.80 |
| ▸ | DRD3 | P35462 | 5/20 | 0.80 |
| ▸ | HRH1 | P35367 | 3/20 | 0.66 |
| ▸ | HRH2 | P25021 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29764232 | 0.90 | HTR7 (1.00) | HTR7DRD2DRD4DRD3HRH1 | |
| SCHEMBL15937769 | 0.90 | HTR7 (1.00) | HTR7DRD2DRD4DRD3HRH1 | |
| SCHEMBL15938480 | 0.89 | HTR7 (1.00) | HTR7DRD2DRD4DRD3HRH1 | |
| SCHEMBL15937599 | 0.88 | HTR7 (1.00) | HTR7DRD2DRD4DRD3HRH1 | |
| SCHEMBL15937713 | 0.85 | HTR7 (1.00) | HTR7DRD2DRD4DRD3HRH1 | |
| SCHEMBL9720681 | 0.82 | MAPK1 (0.78) | HTR7DRD2DRD4DRD3KDM4E | |
| SCHEMBL9720709 | 0.82 | KDM4E (0.71) | HTR7DRD2DRD4DRD3HRH1 | |
| SCHEMBL15938107 | 0.81 | HTR7 (1.00) | HTR7DRD2DRD4DRD3HRH1 | |
| SCHEMBL15937925 | 0.81 | HTR7 (1.00) | HTR7DRD2DRD4DRD3HRH1 | |
| SCHEMBL15937830 | 0.81 | HTR7 (1.00) | HTR7DRD2DRD4DRD3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |