Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002615 | 0.91 | SMN1; SMN2 (0.38) | GAAMAPTPOLBHTTEPHX2 | |
| SCHEMBL9419564 | 0.87 | GNAI3 (0.41) | MAPTPOLBHTTEPHX2SMN1; SMN2 | |
| SCHEMBL11340581 | 0.82 | SMN1; SMN2 (0.42) | GAAMAPTEPHX2SMN1; SMN2EZH2 | |
| SCHEMBL9300620 | 0.79 | HTT (0.41) | GAAMAPTPOLBHTTEPHX2 | |
| SCHEMBL9003139 | 0.78 | EZH2 (0.35) | GAAMAPTPOLBHTTEPHX2 | |
| SCHEMBL9419580 | 0.77 | EPHX1 (0.49) | GAAEPHX2 | |
| SCHEMBL5697678 | 0.76 | MAPT (0.45) | GAAMAPTPOLBEPHX2SMN1; SMN2 | |
| SCHEMBL9002605 | 0.76 | SMN1; SMN2 (0.39) | GAAMAPTPOLBHTTEPHX2 | |
| SCHEMBL9002854 | 0.75 | GAA (0.58) | GAAMAPTPOLBHTT | |
| SCHEMBL9747103 | 0.74 | GNAI3 (0.47) | MAPTEPHX2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132387-A | Polyme bound | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-07-21 | — | — | US | disclosed |