Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.56 |
| ▸ | FGF23 | Q9GZV9 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13917683 | 1.00 | NFE2L2 (0.56) | NFE2L2FGF23TSHRNR1H3RELA | |
| SCHEMBL9720760 | 1.00 | NFE2L2 (0.56) | NFE2L2FGF23TSHRNR1H3RELA | |
| SCHEMBL553822 | 0.91 | NR1H3 (0.44) | NFE2L2FGF23TSHRNR1H3RELA | |
| SCHEMBL21574808 | 0.91 | NR1H3 (0.44) | NFE2L2FGF23TSHRNR1H3RELA | |
| SCHEMBL29392092 | 0.91 | NR1H3 (0.44) | NFE2L2FGF23TSHRNR1H3RELA | |
| SCHEMBL553823 | 0.91 | NR1H3 (0.44) | NFE2L2FGF23TSHRNR1H3RELA | |
| SCHEMBL14319644 | 0.88 | TSHR (0.52) | NFE2L2FGF23TSHRNR1H3RELA | |
| SCHEMBL11486051 | 0.87 | NFE2L2 (0.48) | NFE2L2NR1H3RELAHPGDALDH1A1 | |
| SCHEMBL11486049 | 0.87 | NFE2L2 (0.48) | NFE2L2NR1H3RELAHPGDALDH1A1 | |
| SCHEMBL11484561 | 0.85 | NR1H3 (0.41) | NFE2L2FGF23TSHRNR1H3RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10449174-B2 | Aryl isonitrile compounds as a new class of potent, broad-spectrum antifungal compounds | PURDUE RESEARCH FOUNDATION (US) | 2019-10-22 | — | — | US | disclosed |
| US-20170181997-A1 | ARYL ISONITRILE COMPOUNDS AS A NEW CLASS OF POTENT, BROAD-SPECTRUM ANTIFUNGAL COMPOUNDS | PURDUE RESEARCH FOUNDATION (US) | 2017-06-29 | — | — | US | disclosed |
| US-5152922-A | 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0252009-B1 | 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-08-01 | — | — | EP | disclosed |
| EP-0150441-B1 | 1,4-BIS-(STYRYL)-BENZENES AND THEIR USE AS OPTICAL BRIGHTENER | BAYER AG (DE) | 1987-03-18 | — | — | EP | disclosed |
| EP-0150441-A1 | 1,4-Bis-(styryl)-benzenes and their use as optical brightener | BAYER AG (DE) | 1985-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10449174-B2 | Aryl isonitrile compounds as a new class of potent, broad-spectrum antifungal compounds | AHR, CYP3A4, NAT1 | NFE2L2 3592/4885FGF23 1546/4885TSHR 3640/4885 |
| US-20170181997-A1 | ARYL ISONITRILE COMPOUNDS AS A NEW CLASS OF POTENT, BROAD-SPECTRUM ANTIFUNGAL COMPOUNDS | AHR, CYP3A4, NAT1 | NFE2L2 3592/4885FGF23 1546/4885TSHR 3640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.