Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720771 | 0.94 | TAAR1 (0.40) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL9720876 | 0.92 | TAAR1 (0.40) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL1443909 | 0.89 | ENPP1 (0.39) | GSK3BCLK4MAP4K4PRKACA | |
| SCHEMBL9720787 | 0.84 | ESR2 (0.42) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL9720743 | 0.83 | TAAR1 (0.36) | TAAR1ESR2PDK2DHODHMAOB | |
| SCHEMBL9720745 | 0.80 | DHODH (0.38) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL9720735 | 0.79 | USP7 (0.34) | TAAR1CYP3A4DHODH | |
| SCHEMBL9720784 | 0.79 | ESR2 (0.43) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL9827111 | 0.78 | PDK2 (0.38) | TAAR1ESR2PARP10PARP11PDK2 | |
| SCHEMBL27487056 | 0.76 | TTR (0.39) | TAAR1CYP3A4MC4RAGXTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149707-A | 1-((2-FLUOROPHENYL)(4-FLUOROPHENYL)PHENYLMETHYL)-1H-IMIDAZOLE USEFUL AS ANTIFUNGAL AGENT | J. URIACH & CIA, S.A. (ES) | 1992-09-22 | — | — | US | disclosed |
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | disclosed |
| EP-0352352-A1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1990-01-31 | — | — | EP | disclosed |