Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720768 | 0.87 | ALDH1A1 (0.36) | HIF1AALDH1A1L3MBTL1MAPTDHODH | |
| SCHEMBL1443909 | 0.86 | ENPP1 (0.39) | ALDH1A1MAPK14ENPP1PTGS2PTGS1 | |
| SCHEMBL27487056 | 0.84 | TTR (0.39) | ALDH1A1L3MBTL1CSNK1DCSNK1EMAPK14 | |
| SCHEMBL9720745 | 0.84 | DHODH (0.38) | HIF1AALDH1A1L3MBTL1MAPTDHODH | |
| SCHEMBL9720758 | 0.84 | PDCD1 (0.41) | USP7ALDH1A1L3MBTL1MAPTDHODH | |
| SCHEMBL9720776 | 0.79 | TAAR1 (0.40) | DHODHCYP3A4TAAR1 | |
| SCHEMBL4429566 | 0.77 | PTGS2 (0.43) | ALDH1A1MAPK14PTGS2PTGS1POLB | |
| Methane SCHEMBL27488133 | 0.77 | SMARCA2 (0.37) | ALDH1A1CSNK1DCSNK1EMAPK14CYP1A2 | |
| SCHEMBL8108088 | 0.77 | TAAR1 (0.41) | HIF1AALDH1A1L3MBTL1MAPTCYP1A2 | |
| SCHEMBL9720771 | 0.76 | TAAR1 (0.40) | DHODHCYP3A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | claimed |
| EP-0352352-A1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1990-01-31 | — | — | EP | claimed |
| JP-2048569-A | — | — | None | — | — | JP | disclosed |
| US-5149707-A | 1-((2-FLUOROPHENYL)(4-FLUOROPHENYL)PHENYLMETHYL)-1H-IMIDAZOLE USEFUL AS ANTIFUNGAL AGENT | J. URIACH & CIA, S.A. (ES) | 1992-09-22 | — | — | US | disclosed |
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | disclosed |
| JP-H0248569-A | 1-((2-FLUOROPHENYL)(4-FLUOROPHENYL)PHENYLMETHYL)-1 HIMIDAZOLE | JOTA URIACH & CO SA | 1990-02-19 | — | — | JP | disclosed |
| EP-0352352-A1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1990-01-31 | — | — | EP | disclosed |