Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720784 | 0.95 | ESR2 (0.43) | ESR2TAAR1PDCD1CD274DCLRE1B | |
| SCHEMBL9720773 | 0.92 | PDCD1 (0.43) | ESR2TAAR1PDCD1CD274DCLRE1B | |
| SCHEMBL1443992 | 0.90 | PDCD1 (0.43) | PDCD1CD274GSK3BCLK4PDK2 | |
| SCHEMBL9720776 | 0.84 | TAAR1 (0.40) | ESR2TAAR1DCLRE1BCDC7PIM1 | |
| SCHEMBL9720789 | 0.83 | PDCD1 (0.42) | ESR2TAAR1PDCD1CD274DCLRE1B | |
| SCHEMBL9720771 | 0.81 | TAAR1 (0.40) | ESR2TAAR1DCLRE1BCDC7PIM1 | |
| SCHEMBL18621557 | 0.80 | PDCD1 (0.44) | ESR2TAAR1PDCD1CD274DCLRE1B | |
| SCHEMBL9720792 | 0.80 | PDCD1 (0.42) | ESR2TAAR1PDCD1CD274DCLRE1B | |
| SCHEMBL9720758 | 0.79 | PDCD1 (0.41) | PDCD1CD274PDK2ENPP1CYP3A4 | |
| SCHEMBL9720754 | 0.78 | PDCD1 (0.42) | PDCD1CD274PDK2ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149707-A | 1-((2-FLUOROPHENYL)(4-FLUOROPHENYL)PHENYLMETHYL)-1H-IMIDAZOLE USEFUL AS ANTIFUNGAL AGENT | J. URIACH & CIA, S.A. (ES) | 1992-09-22 | — | — | US | disclosed |
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | disclosed |
| EP-0352352-A1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1990-01-31 | — | — | EP | disclosed |