Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28324137 | 0.95 | TSHR (0.50) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL27753355 | 0.91 | TSHR (0.47) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL27772236 | 0.91 | TSHR (0.47) | TSHRMAPK1CES2MGLLALDH1A1 | |
| Zinc Chloride SCHEMBL27752420 | 0.91 | TSHR (0.47) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL2095276 | 0.87 | NOTUM (0.50) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL6746131 | 0.82 | KIF11 (0.50) | TSHRMAPK1ALDH1A1MAPTNPSR1 | |
| Ethylene SCHEMBL28158839 | 0.81 | TSHR (0.61) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL2091605 | 0.81 | TSHR (0.35) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL62723 | 0.81 | TSHR (0.67) | TSHRMAPK1CES2MGLLALDH1A1 | |
| Fluoride SCHEMBL30661872 | 0.78 | TSHR (0.64) | TSHRMAPK1CES2MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3220 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | claimed |
| US-20240218022-A1 | ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-04 | — | — | US | claimed |
| CN-113754569-B | Intermediate compound and preparation method and application thereof | 四川国为制药有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118206748-A | PCB electroplating additive and preparation method thereof | 广东利尔化学有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118164996-A | Sesquiterpene lactone scaberol C selenoether derivative, preparation method and application thereof | 沈阳药科大学 | 2024-06-11 | — | — | CN | claimed |
| CN-118164997-A | Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof | 沈阳药科大学 | 2024-06-11 | — | — | CN | claimed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| EP-3778576-B1 | 2-CYANOPYRIMIDIN-4-YL CARBAMATE OR UREA DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | HANLIM PHARMACEUTICAL CO LTD (KR) | 2024-04-17 | — | — | EP | claimed |
| CN-117486770-A | 2-cyanoacrylate compound and preparation method and application thereof | 贵州大学 | 2024-02-02 | — | — | CN | claimed |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| EP-0013607-B1 | SUBSTITUTED BICYCLO (2,2,1)HEPTANES AND BICYCLO (2,2,1) HEPT-2-ENES AND THEIR PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-03-23 | — | — | EP | claimed |
| EP-0068823-A1 | Novel phosphoro (di or tri) thioate derivatives, pesticidal compositions containing them and the use of the novel derivatives for combating pests | ROHM AND HAAS COMPANY (US) | 1983-01-05 | — | — | EP | claimed |
| EP-0066378-A1 | Pharmaceutical spiro-hydantoin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-08 | — | — | EP | claimed |
| EP-0065407-A2 | Pharmaceutical spiro-succinimide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-24 | — | — | EP | claimed |
| US-4301167-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | INSTITUT MERIEUX (FR) | 1981-11-17 | — | — | US | claimed |
| EP-0001947-B1 | 2-AMINO-THIAZOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL PREPARATIONS | INSTITUT MERIEUX (FR) | 1981-10-14 | — | — | EP | claimed |
| EP-0028906-A1 | 1'-Substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones, processes for their manufacture and pharmaceutical compositions thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-05-20 | — | — | EP | claimed |
| US-4243405-A | HYDROXYALKYLTRIAZOLES AND DERIVATIVES, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-01-06 | — | — | US | claimed |
| US-4022897-A | 4H-PYRIDO(1,2-A) PYRIMIDIN-4-ONE DERIVATIVES | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | claimed |