Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720960 | 0.83 | L3MBTL1 (0.70) | L3MBTL1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL11177433 | 0.81 | L3MBTL1 (0.52) | L3MBTL1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL9720913 | 0.79 | NPSR1 (0.55) | L3MBTL1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL11371238 | 0.74 | KDM4E (0.53) | L3MBTL1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL9720892 | 0.71 | UBE2N (0.52) | L3MBTL1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL7620695 | 0.70 | KDM4E (0.41) | L3MBTL1MAPTKMT2AMEN1CYP1B1 | |
| SCHEMBL7620692 | 0.70 | KDM4E (0.41) | L3MBTL1MAPTKMT2AMEN1CYP1B1 | |
| SCHEMBL9290377 | 0.68 | CYP1B1 (0.59) | L3MBTL1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL11183672 | 0.68 | L3MBTL1 (0.68) | L3MBTL1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL9721061 | 0.68 | NPSR1 (0.49) | L3MBTL1MAPTKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |