Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RGS12 | O14924 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.51 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | UBE2N | P61088 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9290377 | 0.84 | CYP1B1 (0.59) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL9720907 | 0.83 | L3MBTL1 (0.51) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL9290437 | 0.82 | KMT2A (0.56) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL11183672 | 0.82 | L3MBTL1 (0.68) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL9290283 | 0.81 | NPSR1 (0.52) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL12561203 | 0.80 | ALDH1A1 (0.67) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL12561342 | 0.79 | MAPT (0.53) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL9720966 | 0.79 | NPSR1 (0.79) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL9290350 | 0.77 | MAPT (0.51) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL9290449 | 0.77 | CYP1B1 (0.51) | L3MBTL1NPSR1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |