Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CASP1 | P29466 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329810 | 0.81 | PDE6D (0.57) | PDE6DALDH1A1GAACES2BCHE | |
| SCHEMBL20210861 | 0.79 | ALDH1A1 (0.57) | PDE6DALDH1A1GAANPSR1KMT2A | |
| SCHEMBL9290287 | 0.79 | PDE6D (0.82) | PDE6DALDH1A1GAACES2BCHE | |
| SCHEMBL24254079 | 0.76 | ALDH1A1 (0.54) | PDE6DALDH1A1GAACES2BCHE | |
| SCHEMBL9720939 | 0.75 | KMT2A (0.42) | PDE6DALDH1A1GAANPSR1KMT2A | |
| SCHEMBL20444680 | 0.73 | PDE6D (0.49) | PDE6DALDH1A1GAACES2BCHE | |
| SCHEMBL8363927 | 0.72 | ALDH1A1 (0.58) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL17283708 | 0.71 | PDE6D (0.47) | PDE6DALDH1A1GAACES2BCHE | |
| SCHEMBL18810928 | 0.71 | PDE6D (0.47) | PDE6DALDH1A1GAACES2BCHE | |
| SCHEMBL17283691 | 0.71 | PDE6D (0.47) | PDE6DALDH1A1GAACES2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |