Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | CASP1 | P29466 | 5/20 | 0.42 |
| ▸ | CASP7 | P55210 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720982 | 0.81 | KMT2A (0.60) | KMT2AKDM4ECASP1CASP7GAA | |
| SCHEMBL9720923 | 0.75 | PDE6D (0.54) | KMT2AKDM4ECASP1CASP7GAA | |
| SCHEMBL8363927 | 0.68 | ALDH1A1 (0.58) | KMT2AKDM4ECASP1CASP7GAA | |
| SCHEMBL9720913 | 0.68 | NPSR1 (0.55) | KMT2AKDM4ECASP1GAALMNA | |
| SCHEMBL9720888 | 0.65 | ALDH1A1 (0.47) | KMT2AKDM4ECASP1CASP7GAA | |
| SCHEMBL9720871 | 0.64 | ALDH1A1 (0.50) | KDM4ECASP1GAAALDH1A1L3MBTL1 | |
| SCHEMBL9761358 | 0.64 | KDM4E (0.58) | KMT2AKDM4ECASP1CASP7ALDH1A1 | |
| SCHEMBL2329810 | 0.63 | PDE6D (0.57) | KMT2AKDM4ECASP1CASP7GAA | |
| SCHEMBL3077718 | 0.63 | ALDH1A1 (0.63) | KMT2AKDM4ECASP1CASP7HTT | |
| SCHEMBL281336 | 0.62 | CES1 (0.50) | GAAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |