Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | CASP1 | P29466 | 1/20 | 0.70 |
| ▸ | MPI | P34949 | 1/20 | 0.70 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.70 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HEXA | P06865 | 4/20 | 0.63 |
| ▸ | HEXB | P07686 | 4/20 | 0.63 |
| ▸ | HTR7 | P34969 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | UBE2N | P61088 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | HTR6 | P50406 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131251 | 0.90 | ALDH1A1 (0.71) | HPGDALDH1A1CASP1MPICACNA1B | |
| SCHEMBL9290382 | 0.90 | HEXA (0.64) | HPGDALDH1A1CASP1MPICACNA1B | |
| SCHEMBL24991893 | 0.89 | HPGD (0.60) | HPGDALDH1A1CASP1MPICACNA1B | |
| SCHEMBL9720875 | 0.88 | ALDH1A1 (0.68) | HPGDALDH1A1CASP1MPICACNA1B | |
| SCHEMBL9290383 | 0.86 | HEXA (0.78) | HPGDALDH1A1CASP1MPICACNA1B | |
| SCHEMBL7071975 | 0.86 | ALDH1A1 (0.66) | HPGDALDH1A1CASP1MPICACNA1B | |
| SCHEMBL9290372 | 0.86 | ALDH1A1 (0.57) | HPGDALDH1A1CASP1MPICACNA1B | |
| SCHEMBL12561262 | 0.86 | HPGD (0.57) | HPGDALDH1A1CASP1MPICACNA1B | |
| SCHEMBL9290371 | 0.86 | ALDH1A1 (0.61) | HPGDALDH1A1CASP1MPICACNA1B | |
| SCHEMBL7129147 | 0.86 | HPGD (0.57) | HPGDALDH1A1CASP1MPICACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |