Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 16/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721313 | 0.81 | ERN1 (0.41) | ERN1 | |
| SCHEMBL9721235 | 0.81 | ERN1 (0.41) | ERN1 | |
| SCHEMBL9721357 | 0.81 | TLR8 (0.37) | ERN1 | |
| SCHEMBL9721278 | 0.79 | KDM4E (0.40) | ERN1 | |
| SCHEMBL9721310 | 0.75 | CYP3A4 (0.35) | ERN1CA1CA2 | |
| SCHEMBL9721418 | 0.75 | CA1 (0.36) | CA1CA2 | |
| SCHEMBL10454966 | 0.72 | CYP3A4 (0.35) | ERN1CA1CA2 | |
| SCHEMBL9721344 | 0.70 | CA1 (0.38) | CA1CA2 | |
| SCHEMBL9721275 | 0.68 | TLR8 (0.40) | ERN1 | |
| SCHEMBL28047266 | 0.67 | CA1 (0.46) | ERN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | claimed |
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | claimed |
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | disclosed |
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | disclosed |