Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721297 | 0.87 | CA1 (0.43) | CA1CA2TLR8MAPTMEN1 | |
| SCHEMBL9721302 | 0.82 | TLR8 (0.35) | CA1CA2TLR8MAPTALDH1A1 | |
| SCHEMBL9721311 | 0.78 | MAOA (0.36) | TLR8ESR1ESR2CYP3A4 | |
| SCHEMBL9721291 | 0.78 | TLR8 (0.36) | CA1CA2TLR8MAPTALDH1A1 | |
| SCHEMBL9721245 | 0.75 | MAPT (0.41) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9721344 | 0.72 | CA1 (0.38) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL10454937 | 0.72 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL19126271 | 0.68 | CA1 (0.78) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL29006355 | 0.66 | ESR2 (0.41) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL10454966 | 0.66 | CYP3A4 (0.35) | CA1CA2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | claimed |
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | claimed |