Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.89 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | METAP2 | P50579 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benodanil SCHEMBL18736 | 0.94 | MEN1 (1.00) | MEN1KMT2ATDP1ALDH1A1CYP3A4 | |
| Benodanil SCHEMBL29402073 | 0.94 | MEN1 (1.00) | MEN1KMT2ATDP1ALDH1A1CYP3A4 | |
| Benodanil SCHEMBL28267472 | 0.83 | MEN1 (0.78) | MEN1KMT2ATDP1ALDH1A1CYP3A4 | |
| SCHEMBL1991348 | 0.83 | ALDH1A1 (1.00) | MEN1KMT2ATDP1ALDH1A1CYP3A4 | |
| SCHEMBL45299 | 0.83 | ALDH1A1 (1.00) | MEN1KMT2ATDP1ALDH1A1CYP3A4 | |
| SCHEMBL30516691 | 0.82 | ALDH1A1 (0.65) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL40612 | 0.82 | ALDH1A1 (0.65) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL23070511 | 0.82 | MEN1 (0.71) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL27493749 | 0.82 | MEN1 (0.77) | MEN1KMT2ATDP1ALDH1A1CYP3A4 | |
| SCHEMBL28496803 | 0.82 | MEN1 (0.77) | MEN1KMT2ATDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5129950-A | Modulation of membrane dependent metabolism | A NATTERMANN & CIE GMBH (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0250583-A1 | USE OF MEMBRANE MODULATORS AND PRODUCTS COMPRISING SUCH MEMBRANE MODULATORS | A. Nattermann & Cie. GmbH (DE) | 1988-01-07 | — | — | EP | disclosed |
| CN-87100159-A | The application of film regulatory factor and contain the product of this film regulatory factor | — | 1987-09-16 | — | — | CN | disclosed |
| EP-0231765-A1 | Use of membrane modulators and products comprising such membrane modulators | A. Nattermann & Cie. GmbH (DE) | 1987-08-12 | — | — | EP | disclosed |
| WO-1987004048-A1 | USE OF MEMBRANE MODULATORS AND PRODUCTS COMPRISING SUCH MEMBRANE MODULATORS | A. NATTERMANN & CIE GMBH (DE) | 1987-07-16 | — | — | WO | disclosed |
| EP-0068296-B1 | A NEW FUNGICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE | A. Nattermann & Cie. GmbH (DE) | 1985-12-11 | — | — | EP | disclosed |
| EP-0068296-A1 | A new fungicidal composition, processes for its production and its use | A. Nattermann & Cie. GmbH (DE) | 1983-01-05 | — | — | EP | disclosed |