Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | METAP2 | P50579 | 1/20 | 0.63 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.63 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.63 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.63 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45299 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL13927135 | 0.96 | ALDH1A1 (0.92) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL437231 | 0.93 | ALDH1A1 (0.87) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL12189649 | 0.92 | ALDH1A1 (0.85) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL11266257 | 0.91 | ALDH1A1 (0.83) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL11266259 | 0.91 | ALDH1A1 (0.83) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL328588 | 0.91 | ALDH1A1 (0.82) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL13927138 | 0.90 | ALDH1A1 (0.81) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL1336628 | 0.88 | ALDH1A1 (0.79) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL29360103 | 0.88 | ALDH1A1 (0.79) | ALDH1A1CYP3A4CYP2C9ALOX12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140005049-A1 | ACTIVE COMPOUND COMBINATIONS | ILG KERSTIN (DE) | 2014-01-02 | — | — | US | claimed |
| EP-2515649-A2 | ACTIVE COMPOUND COMBINATIONS | Bayer Intellectual Property GmbH (DE) | 2012-10-31 | — | — | EP | claimed |
| WO-2011080044-A2 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | claimed |
| US-20110152077-A1 | Active compound combinations | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | claimed |
| US-20140005049-A1 | ACTIVE COMPOUND COMBINATIONS | ILG KERSTIN (DE) | 2014-01-02 | — | — | US | disclosed |
| US-20140007297-A1 | BRASSICA PLANTS WITH ALTERED ARCHITECTURE | BAYER CROPSCIENCE NV (BE) | 2014-01-02 | — | — | US | disclosed |
| US-8530381-B2 | Active compound combinations | BAYER CROPSCIENCE AG (DE) | 2013-09-10 | — | — | US | disclosed |
| EP-2566318-A1 | BRASSICA PLANTS WITH ALTERED ARCHITECTURE | Bayer CropScience NV (BE) | 2013-03-13 | — | — | EP | disclosed |
| EP-2515649-A2 | ACTIVE COMPOUND COMBINATIONS | Bayer Intellectual Property GmbH (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011137998-A1 | BRASSICA PLANTS WITH ALTERED ARCHITECTURE | BAYER BIOSCIENCE N.V. (BE) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011080044-A2 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |
| US-20110152077-A1 | Active compound combinations | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152077-A1 | Active compound combinations | BROX, ATL3, AKR7A2 | ALDH1A1 3621/4885CYP3A4 1702/4885CYP2C9 696/4885 |
| US-20140005049-A1 | ACTIVE COMPOUND COMBINATIONS | BROX, ATL3, AKR7A2 | ALDH1A1 3621/4885CYP3A4 1702/4885CYP2C9 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.