Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409460 | 0.83 | SMN1; SMN2 (0.44) | CA1CA2SMN1; SMN2TRPV1ALDH1A1 | |
| SCHEMBL547261 | 0.83 | SMN1; SMN2 (0.44) | CA1CA2SMN1; SMN2TRPV1ALDH1A1 | |
| SCHEMBL547259 | 0.83 | SMN1; SMN2 (0.44) | CA1CA2SMN1; SMN2TRPV1ALDH1A1 | |
| SCHEMBL547260 | 0.83 | SMN1; SMN2 (0.44) | CA1CA2SMN1; SMN2TRPV1ALDH1A1 | |
| SCHEMBL11396528 | 0.81 | PIN1 (0.47) | MTNR1AMTNR1BSMN1; SMN2TRPV1PIN1 | |
| SCHEMBL9621384 | 0.80 | NQO2 (0.48) | NQO2MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL1842495 | 0.78 | MTNR1A (0.56) | NQO2MTNR1AMTNR1B | |
| SCHEMBL30746730 | 0.78 | MTNR1A (0.56) | NQO2MTNR1AMTNR1B | |
| SCHEMBL1844946 | 0.78 | PPARD (0.52) | MTNR1AMTNR1BCA1CA2SMN1; SMN2 | |
| SCHEMBL9466937 | 0.76 | NQO2 (0.61) | NQO2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |