Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874514 | 0.87 | ALOX5 (0.57) | MAPTMAPK1ABCB1TP53SMN1; SMN2 | |
| SCHEMBL182941 | 0.86 | MAPK1 (0.56) | MAPTMAPK1ABCB1TP53SMN1; SMN2 | |
| SCHEMBL1663978 | 0.85 | ALDH1A1 (0.54) | MAPTMAPK1ABCB1TP53SMN1; SMN2 | |
| SCHEMBL4368126 | 0.84 | MAPT (0.67) | MAPTMAPK1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL29484215 | 0.84 | MAPT (0.67) | MAPTMAPK1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL3137381 | 0.83 | MAPT (0.48) | MAPTMAPK1ABCB1TP53SMN1; SMN2 | |
| SCHEMBL375109 | 0.82 | MAPT (0.53) | MAPTMAPK1ABCB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12312144 | 0.82 | PDGFRB (0.57) | MAPTMAPK1ABCB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9306308 | 0.81 | MAPT (0.62) | MAPTMAPK1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL4407574 | 0.81 | ALDH1A1 (0.50) | MAPTMAPK1ABCB1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164111-A | Polymerizable liquid-crystal material and polymers exhibiting liquid-crystal phases | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1992-11-17 | — | — | US | disclosed |