Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.31 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028490 | 0.93 | MAOB (0.32) | MAOBMAP3K7TAB1LMNAGAA | |
| SCHEMBL9722383 | 0.84 | MAOB (0.33) | MAOBMAP3K7TAB1LMNAGAA | |
| SCHEMBL9028554 | 0.82 | MAOB (0.34) | MAOBLMNAGAA | |
| SCHEMBL9028428 | 0.82 | LMNA (0.33) | MAOBMAP3K7TAB1LMNAGAA | |
| SCHEMBL9028421 | 0.82 | LMNA (0.33) | MAOBMAP3K7TAB1LMNAGAA | |
| SCHEMBL9028486 | 0.80 | MAOB (0.33) | MAOBMAP3K7TAB1LMNAGAA | |
| SCHEMBL9028973 | 0.80 | MAOB (0.36) | MAOBLMNAGAA | |
| SCHEMBL9028802 | 0.78 | MAOB (0.36) | MAOBLMNAGAA | |
| SCHEMBL9027245 | 0.78 | MAOB (0.34) | MAOBLMNAGAA | |
| SCHEMBL9028475 | 0.76 | MAOB (0.36) | MAOBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149834-A | Anticholesterol agent and enzyme inhibitors, for curing arteriosclerosis | FUJIREBIO INC. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445827-A2 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO INC. (JP) | 1991-09-11 | — | — | EP | disclosed |