Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 7/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 7/20 | 0.50 |
| ▸ | GSK3B | P49841 | 9/20 | 0.49 |
| ▸ | CDK2 | P24941 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550480 | 0.87 | TARBP2 (0.55) | FBP1GSK3BALDH1A1ADORA2A | |
| SCHEMBL5727790 | 0.87 | FBP1 (0.69) | FBP1GSK3BALDH1A1HPGDHSD17B10 | |
| SCHEMBL9585792 | 0.84 | FBP1 (0.52) | FBP1ALDH1A1HPGDHSD17B10ADORA2A | |
| SCHEMBL3125530 | 0.84 | TARBP2 (0.56) | FBP1ADORA2A | |
| SCHEMBL15173602 | 0.84 | FBP1 (0.52) | FBP1GSK3BCDK2ADORA2A | |
| SCHEMBL9585840 | 0.84 | GAA (0.60) | FBP1ALDH1A1HPGD | |
| SCHEMBL472899 | 0.84 | GSK3B (0.55) | FBP1GSK3BCDK2 | |
| SCHEMBL9722663 | 0.84 | FBP1 (0.52) | FBP1CDC7DBF4GSK3BALDH1A1 | |
| SCHEMBL9722654 | 0.84 | GSK3B (0.55) | FBP1GSK3BCDK2ADORA2A | |
| SCHEMBL3119080 | 0.83 | TARBP2 (0.57) | FBP1GSK3BCDK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106986-A | PREPARATION OF AMINOETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | disclosed |
| EP-0450180-A2 | Process for the preparation of aminoethanol derivatives | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |