Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 2/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722610 | 0.85 | GSK3B (0.53) | FBP1GSK3BNAMPTKDM4EPOLB | |
| SCHEMBL5727790 | 0.85 | FBP1 (0.69) | FBP1GSK3BNPC1RAB9AKDM4E | |
| SCHEMBL9671143 | 0.84 | FBP1 (0.48) | FBP1GSK3BNPC1MEN1KMT2A | |
| SCHEMBL9722608 | 0.84 | FBP1 (0.53) | FBP1GSK3BCDC7DBF4ALDH1A1 | |
| SCHEMBL28550480 | 0.80 | TARBP2 (0.55) | FBP1GSK3BNPC1RAB9AMEN1 | |
| SCHEMBL9722656 | 0.80 | FBP1 (0.46) | FBP1GSK3BNPC1RAB9AKDM4E | |
| SCHEMBL23354396 | 0.79 | CDC7 (0.50) | FBP1GSK3BCDC7DBF4NPC1 | |
| SCHEMBL9586836 | 0.79 | FBP1 (0.51) | FBP1GSK3BKDM4EMAPTMEN1 | |
| SCHEMBL9587212 | 0.79 | ALOX5 (0.52) | FBP1MAPTALDH1A1 | |
| SCHEMBL25292389 | 0.78 | FBP1 (0.46) | FBP1NPC1RAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538059-B | Reaction method for selectively synthesizing oxazole-4-carboxylic ester | 南京工业大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-112538059-A | Reaction method for selectively synthesizing oxazole-4-carboxylic ester | 南京工业大学 | 2021-03-23 | — | — | CN | disclosed |
| US-5106986-A | PREPARATION OF AMINOETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | disclosed |
| EP-0450180-A2 | Process for the preparation of aminoethanol derivatives | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |