Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 6/20 | 0.41 |
| ▸ | GSK3B | P49841 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671143 | 0.87 | FBP1 (0.48) | FBP1TARBP2GAACDK2GSK3B | |
| SCHEMBL6365735 | 0.85 | GAA (0.47) | FBP1GAAKDM4ECDK2GSK3B | |
| SCHEMBL9585840 | 0.85 | GAA (0.60) | FBP1TARBP2GAAKDM4EALDH1A1 | |
| SCHEMBL28550480 | 0.82 | TARBP2 (0.55) | FBP1TARBP2GAAALDH1A1GSK3B | |
| SCHEMBL9585814 | 0.82 | ALOX5 (0.51) | FBP1TARBP2GAACDK2GSK3B | |
| SCHEMBL9722633 | 0.82 | FBP1 (0.45) | FBP1TARBP2GAAALDH1A1HTT | |
| SCHEMBL9722621 | 0.81 | CDK2 (0.45) | FBP1TARBP2GAAALDH1A1HTT | |
| SCHEMBL3125530 | 0.80 | TARBP2 (0.56) | FBP1TARBP2GAAKDM4EHTT | |
| SCHEMBL9585792 | 0.80 | FBP1 (0.52) | FBP1TARBP2GAAKDM4EALDH1A1 | |
| SCHEMBL15173602 | 0.80 | FBP1 (0.52) | FBP1TARBP2GAACDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106986-A | PREPARATION OF AMINOETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | disclosed |
| EP-0450180-A2 | Process for the preparation of aminoethanol derivatives | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |