Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.80 |
| ▸ | RAB9A | P51151 | 11/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | TP53 | P04637 | 7/20 | 0.78 |
| ▸ | HPGD | P15428 | 5/20 | 0.78 |
| ▸ | PKM | P14618 | 3/20 | 0.78 |
| ▸ | MITF | O75030 | 1/20 | 0.78 |
| ▸ | XBP1 | P17861 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374898 | 0.88 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL9722680 | 0.85 | RAB9A (0.77) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL4296002 | 0.82 | RAB9A (0.57) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL4307212 | 0.81 | RAB9A (0.56) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL4299079 | 0.81 | TSHR (0.56) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL9722697 | 0.79 | NPC1 (0.67) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL9722686 | 0.77 | RAB9A (0.73) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL9722714 | 0.77 | RAB9A (0.64) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL9722701 | 0.75 | MEN1 (0.60) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL9722717 | 0.75 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139564-A | Applying postemergence | PARK SANG W (KR) | 1992-08-18 | — | — | US | claimed |
| US-5139564-A | Applying postemergence | PARK SANG W (KR) | 1992-08-18 | — | — | US | disclosed |